Article
Complement Factor H Family Proteins Modulate Monocyte and Neutrophil Granulocyte Functions.
Frontiers in immunology - 1 Jan 2021
Kárpáti Éva, Kremlitzka Mariann, Sándor Noémi, Hajnal Dávid, Schneider Andrea E, Józsi Mihály
Abstract excerpt
Besides being a key effector arm of innate immunity, a plethora of non-canonical functions of complement has recently been emerging. Factor H (FH), the main regulator of the alternative pathway of complement activation, has been reported to bind to various immune cells and regulate their functions, beyond its role in modulating complement activation. In this study we investigated the effect of FH, its alternative...
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