Article

Predictomes: A classifier-curated database of AlphaFold-modeled protein-protein interactions

2024-04-12

Abstract excerpt

<h4>Summary</h4> Protein-protein interactions (PPIs) are ubiquitous in biology, yet a comprehensive structural characterization of the PPIs underlying biochemical processes is lacking. Although AlphaFold-Multimer (AF-M) has the potential to fill this knowledge gap, standard AF-M confidence metrics do not reliably separate relevant PPIs from an abundance of false positive predictions. To address this limitation, w...

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Literature Corpus work: 90b1f9ed-249c-5459-88b9-32c3b18c7095
DOI: 10.1101/2024.04.09.588596

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