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Mitotic chromatin marking governs asymmetric segregation of DNA damage

2023-09-05

Abstract excerpt

<h4>SUMMARY</h4> The faithful segregation of intact genetic material and the perpetuation of chromatin states through mitotic cell divisions are pivotal for maintaining cell function and identity across cell generations. However, most exogenous mutagens generate long-lasting DNA lesions that are segregated during mitosis. How this segregation is controlled is unknown. Here, we uncover a mitotic chromatin-marking...

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Identifiers and source

Literature Corpus work
90622b45-dd13-5c77-8595-9477f586fb7d
DOI
10.1101/2023.09.04.556166
Open publication

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Mitotic chromatin marking governs asymmetric segregation of DNA damageDOI 10.1101/2023.09.04.556166
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