Back to search

Article

An optogenetic toolkit for robust activation of FGF, BMP, & Nodal signaling in zebrafish

2025-04-19

Abstract excerpt

<h4>ABSTRACT</h4> Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in basic and translational research. Here, we present an optogenetic toolkit for signaling manipulation in zebrafish embryos. We introduce a zebrafish-optimized optogenetic FGF signaling activator and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
902d5381-4588-5b9c-8bf9-4353762a3a64
DOI
10.1101/2025.04.17.649426
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An optogenetic toolkit for robust activation of FGF, BMP, & Nodal signaling in zebrafishDOI 10.1101/2025.04.17.649426
Optogenetic Signaling Activation in Zebrafish EmbryosSemantic proximity
A transgenic zebrafish for spatiotemporal optogenetic activation of FGF/ERK signalingSemantic proximity
Optogenetic control of the Bone Morphogenetic Protein signalling pathway through engineered blue light-sensitive receptorsSemantic proximity
Optogenetic manipulation of YAP cellular localisation and functionSemantic proximity
Construction of light-activated neurotrophin receptors using the improved Light-Induced Dimerizer (iLID)Semantic proximity
Protocol to locally express cxcl12a during zebrafish olfactory organ development by combining IR-LEGO with live imaging.Semantic proximity
Real-time observation of light-controlled transcription in living cellsSemantic proximity
A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseasesSemantic proximity
Optical Control of Tumor Induction in the Zebrafish.Semantic proximity
Optogenetic Rescue Reveals Spatiotemporal Rules of Germ-Layer PatterningSemantic proximity
Optimizing photoswitchable MEK.Semantic proximity
Light reaches the very heart of the zebrafish clock.Semantic proximity
Select a neighboring publication to make it the new centre.