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Article

IDH-mutant gliomas with additional class-defining molecular events.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2021

Ahrendsen Jared T, Torre Matthew, Meredith David M, Hornick Jason L, Reardon David A, Wen Patrick Y, Yeo Kee K, Malinowski Seth, Ligon Keith L, Ramkissoon Shakti, Alexandrescu Sanda

Abstract excerpt

The 2016 WHO classifies IDH-mutant gliomas into oligodendroglioma or diffuse astrocytoma based on co-occurring genetic events. Recent literature addresses the concept of stratifying IDH-mutant gliomas based on prognostically significant molecular events. However, the presence of a second class-defining driver alteration in IDH-mutant gliomas has not been systematically described. We searched the sequencing...

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PMID: 33772213
DOI: 10.1038/s41379-021-00795-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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