Article
Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.
Acta neuropathologica - 1 Jul 2018
Shirahata Mitsuaki, Ono Takahiro, Stichel Damian, Schrimpf Daniel, Reuss David E, Sahm Felix, Koelsche Christian, Wefers Annika, Reinhardt Annekathrin, Huang Kristin, Sievers Philipp, Shimizu Hiroaki, Nanjo Hiroshi, Kobayashi Yusuke, Miyake Yohei, Suzuki Tomonari, Adachi Jun-Ichi, Mishima Kazuhiko, Sasaki Atsushi, Nishikawa Ryo, Bewerunge-Hudler Melanie, Ryzhova Marina, Absalyamova Oksana, Golanov Andrey, Sinn Peter, Platten Michael, Jungk Christine, Winkler Frank, Wick Antje, Hänggi Daniel, Unterberg Andreas, Pfister Stefan M, Jones David T W, van den Bent Martin, Hegi Monika, French Pim, Baumert Brigitta G, Stupp Roger, Gorlia Thierry, Weller Michael, Capper David, Korshunov Andrey, Herold-Mende Christel, Wick Wolfgang, Louis David N, von Deimling Andreas
Abstract excerpt
According to the 2016 World Health Organization Classification of Tumors of the Central Nervous System (2016 CNS WHO), IDH-mutant astrocytic gliomas comprised WHO grade II diffuse astrocytoma, IDH-mutant (AIIIDHmut), WHO grade III anaplastic astrocytoma, IDH-mutant (AAIIIIDHmut), and WHO grade IV glioblastoma, IDH-mutant (GBMIDHmut). Notably, IDH gene status has been made the major criterion for classification...
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