Article

Genomic profiles of IDH-mutant gliomas: MYCN amplified IDH-mutant astrocytoma had the worst prognosis and true mixed oligoastrocytoma does not exist

2022-12-29

Abstract excerpt

<h4>Background: </h4> This study aims to find any ambiguous genetic outlier for “oligodendroglioma, IDH-mutant and 1p/19q-codeleted (O_IDH_mut)” and “astrocytoma, IDH-mutant (A_IDH_mut)” and to redefine the genetic landscape of IDH-mutant gliomas. <h4>Methods:</h4> The next-generation sequencing (NGS) using a brain tumor-targeted gene panel, methylation profiles, and clinicopathological features were analyzed in O...

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Literature Corpus work: 2bc877f8-f347-542d-ae8f-9a0e0634b2aa
DOI: 10.21203/rs.3.rs-2385126/v1

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