Article

Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneity

2019-10-17

Abstract excerpt

1 Triple-drug therapies have transformed HIV from a fatal condition to a chronic one. These therapies should prevent HIV drug resistance evolution, because one or more drugs suppress any partially-resistant viruses. In practice, such therapies drastically reduced, but did not eliminate, resistance evolution. In this article, we reanalyze published data from an evolutionary perspective and demonstrate several intri...

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Literature Corpus work: 8eb4020d-983a-520b-a6f3-51df58a87238
DOI: 10.1101/807560

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