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Article

Evolution of HIV-1 in a patient population failing multiple-drug therapy.

Microbiology and immunology - 1 Sept 2009

Hong Shaolin, Cao Jingjiang, Tu Ya-ting

Abstract excerpt

To understand the evolutionary pathway of the multi-drug-resistant virus HIV-1 under drug-induced selection pressure, plasma from seven patients from baseline to different intervals post-treatment failure were used in RT-PCR protocols. Multiple clones were sequenced for each time point. Drug-resistant mutations were detected in five patients. Phylogenetic analysis showed that at different time points, viral...

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Identifiers

PMID: 19703248
DOI: 10.1111/j.1348-0421.2009.00153.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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