Article
A decade of HIV-1 drug resistance in the United States: trends and characteristics in a large protease/reverse transcriptase and co-receptor tropism database from 2003 to 2012.
Antiviral therapy - 1 Jan 2014
Paquet Agnes C, Solberg Owen D, Napolitano Laura A, Volpe Joseph M, Walworth Charles, Whitcomb Jeannette M, Petropoulos Christos J, Haddad Mojgan
Abstract excerpt
BACKGROUND: Drug resistance testing and co-receptor tropism determination are key components of the management of antiretroviral therapy for HIV-1-infected individuals. The purpose of this study was to examine trends of HIV-1 resistance and viral evolution in the past decade by surveying a large commercial patient testing database. METHODS: Temporal trends of drug resistance, viral fitness and co-receptor usage...
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