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Article

Nested model reveals potential amplification of an HIV epidemic due to drug resistance

16 Nov 2012

Abstract excerpt

The use of antiretroviral therapy (ART) is the most efficient measure in controlling the HIV epidemic. However, emergence of drug-resistant strains can reduce the potential benefits of ART. The viral dynamics of drug-sensitive and drug-resistant strains at the individual level may play a crucial role in the emergence and spread of drug resistance in a population. We investigate the effect of the viral dynamics...

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Identifiers

PMID: 23438429
DOI: 10.1016/j.epidem.2012.11.002

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