Article

Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain

2021-12-21

Abstract excerpt

<title>Abstract</title> <p>Despite an estimated twin heritability of ~50%, genome-wide association studies (GWAS) of opioid use disorder (OUD) have revealed few genome-wide significant (GWS) loci, with replicated findings only in European-ancestry individuals. To identify novel loci, including those in non-European ancestries, and improve our understanding of the biology of OUD, we conducted a cross-ancestry meta...

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Literature Corpus work: 8eac971c-7fc6-5d99-b153-87985529f7be
DOI: 10.21203/rs.3.rs-1167873/v1

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