Article

A mathematical model of flow-mediated coagulation identifies factor V as a modifier of thrombin generation in hemophilia A:

2018-12-18

Abstract excerpt

Hemophilia A is a bleeding disorder categorized as severe, mild, and moderate deficiencies in factor VIII (FVIII). Within these categories the variance in bleeding severity is significant and the origins unknown. The number of parameters that could modify bleeding are so numerous that experimental approaches are not feasible for considering all possible combinations. Consequently, we turn to a mathematical model o...

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Literature Corpus work: 8e8afe3c-3c67-5196-84b4-b0f77a1a6691
DOI: 10.1101/495374

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