Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thrombin activatable fibrinolysis inhibitor activation and bleeding in haemophilia A.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 May 2012

Foley J H, Nesheim M E, Rivard G E, Brummel-Ziedins K E

Abstract excerpt

Individuals with haemophilia A exhibit bleeding tendencies that are not always predicted by their factor (F)VIII level. It has been suggested that bleeding in haemophilia is due not only to defective prothrombin activation but also aberrant fibrinolysis. Thrombin activatable fibrinolysis inhibitor (TAFI) activation was measured in tissue factor (TF)-initiated blood coagulation in blood samples of 28 haemophiliacs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hemorrhage
Share to Blood Coagulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carboxypeptidase B2

Share to Enzyme Activation

Share to Fibrinolysis

Share to Hemophilia A

Share to Phenotype

Share to Thrombin

Source

Open in PubMed Open full text

Identifiers

PMID: 21933309
DOI: 10.1111/j.1365-2516.2011.02648.x
PMCID: PMC3289731

Genes

TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thrombin activatable fibrinolysis inhibitor activation and bleeding in haemophilia A.PMID 21933309Read ↗

Thrombin generation and bleeding in haemophilia A.Semantic proximity Read ↗

Regulation of fibrinolysis by thrombin activatable fibrinolysis inhibitor, an unstable carboxypeptidase B that unites the pathways of coagulation and fibrinolysis.Semantic proximity Read ↗

How to Capture the Bleeding Phenotype in FXI-Deficient Patients.Semantic proximity Read ↗

Clinical utility of activated partial thromboplastin time clot waveform analysis and thrombin generation test in the evaluation of bleeding phenotype in Hemophilia A.Semantic proximity Read ↗

Bleeding phenotype of patients with moderate haemophilia A and B assessed by thromboelastometry and thrombin generation.Semantic proximity Read ↗

Profibrinolytic effects of rivaroxaban are mediated by thrombin-activatable fibrinolysis inhibitor and are attenuated by a naturally occurring stabilizing mutation in enzyme.Semantic proximity Read ↗

Sample conditions determine the ability of thrombin generation parameters to identify bleeding phenotype in FXI deficiency.Semantic proximity Read ↗

Effect of fibrinolysis on bleeding phenotype in moderate and severe von Willebrand disease.Semantic proximity Read ↗

Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B.Semantic proximity Read ↗

Factor IX-Padua enhances the fibrinolytic resistance of plasma clots.Semantic proximity Read ↗

Factor XIII and Fibrin Clot Properties in Acute Venous Thromboembolism.Semantic proximity Read ↗

Coagulation activation-induced fibrinolysis biomarker changes depend on thrombophilic risk factors and their clinical phenotype: an interventional <i>in vivo</i> studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.