Article
Comprehensive evaluation of deconvolution methods for human brain gene expression
2020-06-01
Abstract excerpt
Gene expression measurements, similar to DNA methylation and proteomic measurements, are influenced by the cellular composition of the sample analysed. Deconvolution of bulk transcriptome data aims to estimate the cellular composition of a sample from its gene expression data, which in turn can be used to correct for composition differences across samples. Although a multitude of deconvolution methods have been de...
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Identifiers and source
- Literature Corpus work
- 0e9106cc-d260-5c4c-a78a-079e07146185
- DOI
- 10.1101/2020.06.01.126839
