Article
Developmental patterning genes and their conserved functions: from model organisms to humans.
Molecular genetics and metabolism - 1 Feb 2000
Veraksa A, Del Campo M, McGinnis W
Abstract excerpt
Molecular and genetic evidence accumulated during the past 20 years in the field of developmental biology indicates that different animals possess many common genetic systems for embryonic patterning. In this review we describe the conserved functions of such developmental patterning genes and their relevance for human pathological conditions. Special attention is given to the Hox genetic system, involved in...
Topics
- Animals
- Biological Evolution
- Caenorhabditis elegans
- Congenital Abnormalities
- Drosophila
- Eye
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Heart
- Humans
- Mice
- Mutation
