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Article

Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis.

Developmental biology - 15 Nov 2006

Nolte Christof, Rastegar Mojgan, Amores Angel, Bouchard Maxime, Grote David, Maas Richard, Kovacs Erzsebet Nagy, Postlethwait John, Rambaldi Isabel, Rowan Sheldon, Yan Yi-Lin, Zhang Feng, Featherstone Mark

Abstract excerpt

The antero-posterior (AP) and dorso-ventral (DV) patterning of the neural tube is controlled in part by HOX and PAX transcription factors, respectively. We have reported on a neural enhancer of Hoxd4 that directs expression in the CNS with the correct anterior border in the hindbrain. Comparison to the orthologous enhancer of zebrafish revealed seven conserved footprints including an obligatory retinoic acid...

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Share to Central Nervous System
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptors, Retinoic Acid

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Source

Identifiers

PMID: 17010333
DOI: 10.1016/j.ydbio.2006.08.061

Genes

PAX6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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