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Article

Distinct requirements for <i>wnt9a</i> and <i>irf6</i> in extension and integration mechanisms during zebrafish palate morphogenesis

16 Nov 2012

Abstract excerpt

Development of the palate in vertebrates involves cranial neural crest migration, convergence of facial prominences and extension of the cartilaginous framework. Dysregulation of palatogenesis results in orofacial clefts, which represent the most common structural birth defects. Detailed analysis of zebrafish palatogenesis revealed distinct mechanisms of palatal morphogenesis: extension, proliferation and...

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PMID: 23154410
DOI: 10.1242/dev.080473

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