Article

Somatic mutations reveal widespread mosaicism and mutagenesis in human placentas

2021-01-27

Abstract excerpt

<h4>ABSTRACT</h4> Clinical investigations of human fetuses have revealed that placentas occasionally harbour chromosomal aberrations that are absent from the fetus 1 . The basis of this genetic segregation of the placenta, termed confined placental mosaicism, remains unknown. Here, we investigated the phylogeny of human placentas reconstructed from somatic mutations, using whole genome sequencing of 86 placental...

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Literature Corpus work: 8de8de69-c120-5b05-9065-a8c7e045e1c2
DOI: 10.1101/2021.01.26.428217

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