Article

Deep Genome Sequencing Uncovers Extensive Genetic Heterogeneity in Early Human Placentas

2024-10-01

Abstract excerpt

<title>Abstract</title> <p>Placental biopsy in early pregnancy is widely used in prenatal genetic diagnostics as a surrogate for fetal tissue. Confined placental chromosomal mosaicism is a well-documented phenomenon causing genetic discrepancies between the fetus and placenta. Although comprehensive sequencing methods are becoming popular for prenatal screening of monogenic disorders, knowledge of concordance bet...

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Literature Corpus work: 7ce019c6-f62a-5696-b98a-bd30e177229d
DOI: 10.21203/rs.3.rs-5140201/v1

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