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Article

Extensive load of somatic CNVs in the human placenta

10 Feb 2015

Abstract excerpt

Placenta is a temporary, but indispensable organ in mammalian pregnancy. From its basic nature, it exhibits highly invasive tumour-like properties facilitating effective implantation through trophoblast cell proliferation and migration, and a critical role in pregnancy success. We hypothesized that similarly to cancer, somatic genomic rearrangements are promoted in the support of placental function. Here we...

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PMID: 25666259
DOI: 10.1038/srep08342

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