Article

Signalome-wide mapping of the NFκB pathway in T-cells reveals novel targets for immunotherapy

2026-02-18

Abstract excerpt

Cell signalling networks govern fundamental cellular processes yet remain incompletely defined. Moreover, what is known is biased toward a limited subset of well-characterised components. Phosphoprotein-based interrogation methods, including mass spectrometry and targeted phosphosite panels, have limited utility in physiological settings dependent on cell–cell interactions because the signalling fluxes can be diff...

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Identifiers and source

Literature Corpus work: 8dc54c9d-177c-585a-9c91-87cab058c362
DOI: 10.64898/2026.02.16.706160

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