Article

PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis

2023-11-17

Abstract excerpt

<h4>Background</h4> PD-1 is an immune checkpoint on T cells and interventions to block this receptor result in T cell activation and enhanced immune response to tumors. Paired to that, and despite a decade of research, approaches to treat autoimmunity with PD-1 agonists still need to be more successful. To resolve this, new methods must be developed to augment PD-1 function beyond engaging the receptor. <h4>Metho...

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Literature Corpus work: b83a3ff4-4781-50bd-8b48-c433d4c9c691
DOI: 10.1101/2023.11.16.566893

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