Article

Delineation of signaling routes that underlie differences in macrophage phenotypic states

2024-01-14

Abstract excerpt

Macrophages represent a major immune cell type in tumor microenvironments, they exist in multiple functional states and are of a strong interest for therapeutic reprogramming. While signaling cascades defining pro-inflammatory macrophages are better characterized, pathways that drive polarization in immunosuppressive macrophages are incompletely mapped. Here, we performed an in-depth characterization of signaling...

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Literature Corpus work: f70b2d25-6c03-579e-83f1-26136f187f82
DOI: 10.1101/2024.01.12.574349

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