Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systematic comparative study of computational methods for HLA typing from next-generation sequencing.

HLA - 1 Jun 2021

Yu Yuechun, Wang Ke, Fahira Aamir, Yang Qiangzhen, Sun Renliang, Li Zhiqiang, Wang Zhuo, Shi Yongyong

Abstract excerpt

The human leukocyte antigen (HLA) system plays an important role in hematopoietic stem cell transplantation (HSCT) and organ transplantations, immune disorders as well as oncological immunotherapy. However, HLA typing remains a challenging task due to the high level of polymorphism and homology among HLA genes. Based on the high-throughput next-generation sequencing data, new HLA typing algorithms and software...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Renal Transplantation Outcomes and Treatments

Share to Sequence Analysis, DNA

Share to T-cell and B-cell Immunology

Share to vaccines and immunoinformatics approaches

Source

Identifiers

PMID: 33655664
DOI: 10.1111/tan.14244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systematic comparative study of computational methods for HLA typing from next-generation sequencing.PMID 33655664Read ↗

Bioinformatics Strategies, Challenges, and Opportunities for Next Generation Sequencing-Based HLA GenotypingSemantic proximity Read ↗

Benchmarking freely available human leukocyte antigen typing algorithms across varying genes, coverages and typing resolutionsSemantic proximity Read ↗

Recent Advances of Human Leukocyte Antigen (HLA) Typing Technology Based on High-Throughput Sequencing.Semantic proximity Read ↗

Benchmarking HLA genotyping from whole genome sequencing across multiple sequencing technologiesSemantic proximity Read ↗

Evaluation of computational programs to predict HLA genotypes from genomic sequencing data.Semantic proximity Read ↗

Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data.Semantic proximity Read ↗

Benchmarking the Human Leukocyte Antigen Typing Performance of Three Assays and Seven Next-Generation Sequencing-Based Algorithms.Semantic proximity Read ↗

Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data.Semantic proximity Read ↗

High-throughput, high-fidelity HLA genotyping with deep sequencing.Semantic proximity Read ↗

HLA-HD: An accurate HLA typing algorithm for next-generation sequencing data.Semantic proximity Read ↗

Benchmarking the HLA typing performance of three HLA assays and seven NGS-based HLA algorithmsSemantic proximity Read ↗

A rigorous benchmarking of alignment-based HLA typing algorithms for RNA-seq dataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.