Article

PATZ1 Reinstates a Growth-Permissive Chromatin Landscape in Adult Corticospinal Neurons After Injury

2025-05-18

Abstract excerpt

<h4>Background</h4> The failure of axon regeneration in the adult central nervous system represents a major barrier to recovery from spinal cord injury and neurodegenerative disease. Pro-growth transcription factors can promote regenerative responses, but their effects remain partial, suggesting that additional restraints must be relieved for these factors to achieve their full potential. The chromatin landscape...

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Literature Corpus work: 8d75557d-0496-5ca7-86ad-cd9712160d5f
DOI: 10.1101/2025.05.14.654166

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