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Article

Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury.

Cell reports - 12 Sept 2017

Arthur-Farraj Peter J, Morgan Claire C, Adamowicz Martyna, Gomez-Sanchez Jose A, Fazal Shaline V, Beucher Anthony, Razzaghi Bonnie, Mirsky Rhona, Jessen Kristjan R, Aitman Timothy J

Abstract excerpt

Repair Schwann cells play a critical role in orchestrating nerve repair after injury, but the cellular and molecular processes that generate them are poorly understood. Here, we perform a combined whole-genome, coding and non-coding RNA and CpG methylation study following nerve injury. We show that genes involved in the epithelial-mesenchymal transition are enriched in repair cells, and we identify several long...

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Identifiers

PMID: 28903050
DOI: 10.1016/j.celrep.2017.08.064
PMCID: PMC5608958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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