Article

Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a interneurons

2024-12-06

Abstract excerpt

<h4>Summary</h4> During development, early regionalization segregates lineages and directs diverse cell fates. Sometimes, however, distinct progenitors produce analogous cell types. For example, V2a neurons, are excitatory interneurons that emerge from different anteroposterior progenitors. V2a neurons demonstrate remarkable plasticity after spinal cord injury and improve motor function, showing potential for cel...

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Literature Corpus work: 030a895f-bf4f-5b53-be5c-671d1dc1865a
DOI: 10.1101/2024.12.03.626573

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