Article
AK098656, a Novel Vascular Smooth Muscle Cell-Dominant Long Noncoding RNA, Promotes Hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2018
Jin Ling, Lin Xianjuan, Yang Lei, Fan Xiaofang, Wang Wenjie, Li Shuangyue, Li Jing, Liu Xiaoyan, Bao Minghui, Cui Xiao, Yang Jichun, Cui Qinghua, Geng Bin, Cai Jun
Abstract excerpt
Recent studies reported some long noncoding RNAs (lncRNAs)-mediated vascular smooth muscle cells (VSMCs) phenotypic switch, which was a common pathophysiological process of vascular diseases. However, whether human-specific expressed lncRNAs would modulate VSMCs phenotype and participate into the pathogenesis of essential hypertension remains unclear. By comparing the circulating lncRNAs expression profiles...
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