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Uncertainty-Aware Gene Rankings Reveal Key Players in Coexpression Networks

2025-12-16

Abstract excerpt

<h4>Motivation</h4> Key genes of a biological system are often prioritized by computing network science measures on a coexpression network inferred from transcriptomic data. But human population heterogeneity and modest sample sizes introduce uncertainty in the inferred coexpression network. Earlier studies have estimated this uncertainty using bootstrap resampling or similar approaches, but fewer have investigat...

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Literature Corpus work
48f15d4f-2cab-594f-b379-fa387e84ba5e
DOI
10.64898/2025.12.13.694156
Open publication

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