Article

Genetic, inflammatory, and epithelial cell differentiation factors control expression of human calpain-14

2018-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Eosinophilic esophagitis (EoE) is a chronic, food-driven allergic disease resulting in eosinophilic esophageal inflammation. We recently found that EoE susceptibility is associated with genetic variants in the promoter of CAPN14 , a gene with reported esophagus-specific expression. CAPN14 is dynamically up-regulated as a function of EoE disease activity and after exposure of epithelial cells t...

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Literature Corpus work: 8c1dfafd-84ce-53cf-b070-6072a94daff5
DOI: 10.1101/359638

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