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Article

Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies.

The Journal of allergy and clinical immunology - 1 Jul 2011

Sherrill Joseph D, Rothenberg Marc E

Abstract excerpt

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus that is compounded by both genetic predisposition and aberrant responses to environmental antigens, particularly those that are food derived. Data have indicated a unique transcriptional response in vivo that defines EoE and that appears to be partially attributable to the T(H)2 cytokine IL-13. Moreover, a number of genetic risk...

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Identifiers

PMID: 21570716
DOI: 10.1016/j.jaci.2011.03.046
PMCID: PMC3129465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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