Article

Acid-Base Homeostasis and Implications to the Phenotypic Behaviors of Cancer

2022-03-07

Abstract excerpt

Acid-base homeostasis is a fundamental property of living cells and its persistent disruption in human cells can lead to a wide range of diseases. We have conducted computational modeling and analysis of transcriptomic data of 4750 human tissue samples of nine cancer types in the TCGA database. Built on our previous study, we have quantitatively estimated the (average) production rate of OH − by cytosolic Fenton...

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Identifiers and source

Literature Corpus work: 8c0a2377-752a-53ce-8807-70353a71e780
DOI: 10.1101/2022.03.04.482927

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