Article

Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer

2022-10-28

Abstract excerpt

<h4>ABSTRACT</h4> Glucose and glutamine are major carbon and energy sources that promote the fast proliferation of cancer cells. Metabolic shifs observed on cell line or mouse models may not reflect the general metabolic shifts in real human cancer tissue. In this study, we conducted a computational characterization of the flux distribution and variations of the central energy metabolism and key branches in a pan...

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Literature Corpus work: b8a5c9fa-4866-515f-88b3-fafa57b31b15
DOI: 10.1101/2022.10.27.514080

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