Article

Single-cell Transcriptomics of Postimplantation Embryos: Unveiling Aneuploidy Effects and Lineage Dynamics

2024-03-22

Abstract excerpt

<title>Abstract</title> <p>Transfer of aneuploid human embryos, as defined by the presence of > 80% cells with an abnormal chromosome complement, is clinically associated with pregnancy loss or congenital abnormalities. However, the transfer of diploid-aneuploid mosaic embryos can lead to healthy live births, indicating the early presence of aneuploid cells might not necessarily compromise embryo developmental co...

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Literature Corpus work: 8be82ce9-0e6d-531d-8a71-0d7abcca765d
DOI: 10.21203/rs.3.rs-4111897/v1

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