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Human blastocysts of normal and abnormal karyotypes display distinct transcriptome profiles

2 Oct 2018

Abstract excerpt

Unveiling the transcriptome of human blastocysts can provide a wealth of important information regarding early embryonic ontology. Comparing the mRNA production of embryos with normal and abnormal karyotypes allows for a deeper understanding of the protein pathways leading to viability and aberrant fetal development. In addition, identifying transcripts specific for normal or abnormal chromosome copy number could...

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PMID: 30297919
DOI: 10.1038/s41598-018-33279-0

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