Article

Control of 3ʹ splice site selection by the yeast splicing factor Fyv6

2024-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Pre-mRNA splicing is catalyzed in two steps: 5ʹ splice site (SS) cleavage and exon ligation. A number of proteins transiently associate with spliceosomes to specifically impact these steps (1 st and 2 nd step factors). We recently identified Fyv6 (FAM192A in humans) as a 2 nd step factor in S. cerevisiae ; however, we did not determine how widespread Fyv6’s impact is on the transcriptome. To...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8ba18163-d10d-57c2-b3df-b4149875ea0b
DOI: 10.1101/2024.05.04.592262

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Control of 3ʹ splice site selection by the yeast splicing factor Fyv6DOI 10.1101/2024.05.04.592262Read

Biochemical and Genetic Evidence Supports Fyv6 as a Second-Step Splicing Factor in <i>Saccharomyces cerevisiae</i>Semantic proximity Read

Control of 3’ Splice Site Selection in <i>S. cerevisiae</i> by a Highly Conserved Amino Acid within the Prp8 α-finger DomainSemantic proximity Read

Control of 3' splice site selection in S. cerevisiae by a highly conserved amino acid within the Prp8 α-finger domain.Semantic proximity Read

The Prp19C subunits Cwc15 and Syf2 function in TREX occupancy and transcription elongationSemantic proximity Read

Coupling of spliceosome complexity to intron diversitySemantic proximity Read

The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.Semantic proximity Read

Spt5's central KOW domains and the Pol II stalk collaborate to regulate chromatin and 3'-end processing in Saccharomyces cerevisiae.Semantic proximity Read

Characterization of Cwc2, U6 snRNA, and Prp8 interactions destabilized by Prp16 ATPase at the transition between the first and second steps of splicing.Semantic proximity Read

Structure of the yeast spliceosomal postcatalytic P complex.Semantic proximity Read

CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome.Semantic proximity Read

Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interactionSemantic proximity Read

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts.Semantic proximity Read