Article

Control of 3’ Splice Site Selection in <i>S. cerevisiae</i> by a Highly Conserved Amino Acid within the Prp8 α-finger Domain

2025-06-20

Abstract excerpt

<h4>ABSTRACT</h4> Precise recognition of the boundaries between exons and introns (splice sites, SS) is essential for the fidelity of gene expression. In contrast with the 5’SS, the consensus 3’SS sequence in both S. cerevisiae and humans is just three nucleotides long: YAG. How the correct 3’SS is chosen among many possible alternates by the spliceosome is often unclear but likely involves proofreading by the P...

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Literature Corpus work: 3dc5fac3-f6b6-5208-a468-1c3ba5192877
DOI: 10.1101/2025.06.16.659908

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