Article

Coupling of spliceosome complexity to intron diversity

2021-03-20

Abstract excerpt

<h4>SUMMARY</h4> We determined that over 40 spliceosomal proteins are conserved between many fungal species and humans but were lost during the evolution of S. cerevisiae , an intron-poor yeast with unusually rigid splicing signals. We analyzed null mutations in a subset of these factors, most of which had not been investigated previously, in the intron-rich yeast Cryptococcus neoformans. We found they govern s...

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Literature Corpus work: d8fac373-0ae8-521c-b958-cc1f574638ab
DOI: 10.1101/2021.03.19.436190

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