Article

Selecting causal risk factors from high-throughput experiments using multivariable Mendelian randomization

2018-08-21

Abstract excerpt

Modern high-throughput experiments provide a rich resource to investigate causal determinants of disease risk. Mendelian randomization (MR) is the use of genetic variants as instrumental variables to infer the causal effect of a specific risk factor on an outcome. Multivariable MR is an extension of the standard MR framework to consider multiple potential risk factors in a single model. However, current implementa...

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Literature Corpus work: 8b950a8d-0051-59e0-aabc-917d14a32a02
DOI: 10.1101/396333

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