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Article

Two-Sample Multivariable Mendelian Randomization Analysis Using R.

Current protocols - 1 Dec 2021

Rasooly Danielle, Peloso Gina M

Abstract excerpt

Mendelian randomization is a framework that uses measured variation in genes for assessing and estimating the causal effect of an exposure on an outcome. Multivariable Mendelian randomization is an extension that can assess the causal effect of multiple exposures on an outcome, and can be advantageous when considering a set (>1) of potentially correlated candidate risk factors in evaluating the causal effect of...

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PMID: 34936225
DOI: 10.1002/cpz1.335
PMCID: PMC8767787

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