Article

MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

2016-12-16

Abstract excerpt

Published genetic associations can be used to infer causal relationships between phenotypes, bypassing the need for individual-level genotype or phenotype data. We have curated complete summary data from 1094 genome-wide association studies (GWAS) on diseases and other complex traits into a centralised database, and developed an analytical platform that uses these data to perform Mendelian randomization (MR) tests...

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Literature Corpus work: 4fc7a581-6171-5ea2-ba84-55aac92a30fc
DOI: 10.1101/078972

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