Article

Residues in HLA class I that Account for Variation of the HIV Host Response Distinctly Modulate Interactions with TCR and KIRs

2022-09-27

Abstract excerpt

<title>Abstract</title> <p>Polymorphisms in human leukocyte antigen (<italic>HLA</italic>) genes strongly influence outcomes to HIV infection. However, the underlying mechanisms by which certain alleles mediate protection is not well understood. Here we systematically investigate residues within HLA class I molecules (at positions 67, 70, 97 and 156) that have been demonstrated by genetic studies to explain the o...

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Literature Corpus work: 8b7f9367-8149-55b9-be40-a2abd84caa89
DOI: 10.21203/rs.3.rs-2105002/v1

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Residues in HLA class I that Account for Variation of the HIV Host Response Distinctly Modulate Interactions with TCR and KIRsDOI 10.21203/rs.3.rs-2105002/v1Read

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