Article

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression

2019-05-24

Abstract excerpt

<h4>Introduction</h4> It’s imperative to understand the specific and shared aetiologies of major depression and cardio-metabolic disease, as both traits are frequently comorbid and each represents a major burden to society. This study examined whether there is a genetic association between major depression and cardio-metabolic traits and if this association is stratified by age at onset for major depression. <h4>...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8b5f50af-a616-5aa9-ab2a-fca0a18314d2
DOI: 10.1101/645077

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depressionDOI 10.1101/645077Read

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.Semantic proximity Read

Clustering of major depressive disorder genetic instruments identifies distinct and directionally opposing effects on cardiometabolic riskSemantic proximity Read

Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study.Semantic proximity Read

Shared genetic loci between depression and cardiometabolic traits.Semantic proximity Read

Genetic heterogeneity affects the risk of incident depression, comorbidity, and response to environment: A prospective trajectory study.Semantic proximity Read

Sex differences in the associations of genetic, sociodemographic and cardiovascular risk factors with depression in the Canadian Longitudinal Study on Aging (CLSA)Semantic proximity Read

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.Semantic proximity Read

Symptom-specific genetics reveal heterogeneity within major depressive disorderSemantic proximity Read

Differential associations of various depression-related phenotypes with cardiometabolic risks: Identification of shared genetic factors and implications for drug repositioningSemantic proximity Read

Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registriesSemantic proximity Read

Unraveling the Genetic Interplay and Therapeutic Potentials between Major Depressive Disorder and Metabolic Syndrome: Multi-Ancestry and Multi-Trait Genome-Wide Association AnalysesSemantic proximity Read

Triglyceride-glucose index, genetic predisposition, and incident depression: a prospective cohort study from the UK Biobank.Semantic proximity Read