Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study.

Diabetologia - 1 Jul 2020

Tang Bowen, Yuan Shuai, Xiong Ying, He Qiqiang, Larsson Susanna C

Abstract excerpt

AIMS/HYPOTHESIS: Observational studies have shown a bidirectional association between major depressive disorder (MDD) and cardiometabolic diseases. We conducted a two-sample bidirectional Mendelian randomisation (MR) study to assess the causal associations of MDD with type 2 diabetes, coronary artery disease (CAD) and heart failure and vice versa. METHODS: We extracted summary-level data for MDD, type 2 diabetes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Artery Disease
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Associations and Epidemiology

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 32270255
DOI: 10.1007/s00125-020-05131-6
PMCID: PMC7286869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study.PMID 32270255Read ↗

Causal association between major depressive disorder and coronary heart disease: a two-sample bidirectional mendelian randomization studySemantic proximity Read ↗

Clustering of major depressive disorder genetic instruments identifies distinct and directionally opposing effects on cardiometabolic riskSemantic proximity Read ↗

Major depression disorder and heart failure: A two-sample bidirectional Mendelian randomization study.Semantic proximity Read ↗

The association between depression and metabolic syndrome and its components: a bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depressionSemantic proximity Read ↗

Causes and consequences of major depressive disorder: An encompassing Mendelian randomization studySemantic proximity Read ↗

Sex-Specific causal dynamic between Insulin resistance and MDD, a bidirectional Mendelian randomization studySemantic proximity Read ↗

Bidirectional Mendelian Randomization and Multiphenotype GWAS Show Causality and Shared Pathophysiology Between Depression and Type 2 Diabetes.Semantic proximity Read ↗

Bi-directional Mendelian randomization and multi-phenotype GWAS show causality and shared pathophysiology between depression and type 2 diabetesSemantic proximity Read ↗

Depression and type 2 diabetes risk: a Mendelian randomization study.Semantic proximity Read ↗

Heartache and Heartbreak: An Observational and Mendelian Randomization Study.Semantic proximity Read ↗

Phenome-wide investigation of bidirectional causal relationships between major depressive disorder and common human diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.