Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.

PLoS genetics - 1 Jun 2023

Baltramonaityte Vilte, Pingault Jean-Baptiste, Cecil Charlotte A M, Choudhary Priyanka, Järvelin Marjo-Riitta, Penninx Brenda W J H, Felix Janine, Sebert Sylvain, Milaneschi Yuri, Walton Esther

Abstract excerpt

Coronary artery disease (CAD), type 2 diabetes (T2D) and depression are among the leading causes of chronic morbidity and mortality worldwide. Epidemiological studies indicate a substantial degree of multimorbidity, which may be explained by shared genetic influences. However, research exploring the presence of pleiotropic variants and genes common to CAD, T2D and depression is lacking. The present study aimed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Disease Management Strategies
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Associations and Epidemiology

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 37390107
DOI: 10.1371/journal.pgen.1010508
PMCID: PMC10343069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.PMID 37390107Read ↗

Combining polygenic risk scores to understand genetic liability to physical-mental health multimorbidity in UK Biobank.Semantic proximity Read ↗

Combining polygenic risk scores to understand genetic liability to physical-mental health multimorbidity in UK BioBankSemantic proximity Read ↗

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depressionSemantic proximity Read ↗

The multivariate genetic architecture of psychiatric and insulin resistance multimorbiditySemantic proximity Read ↗

Genome-wide association study of cardiometabolic multimorbidity in the UK Biobank.Semantic proximity Read ↗

Genetic heterogeneity affects the risk of incident depression, comorbidity, and response to environment: A prospective trajectory study.Semantic proximity Read ↗

Causal association of modifiable factors with cardiometabolic multimorbidity: an exposome-wide Mendelian randomization investigation.Semantic proximity Read ↗

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.Semantic proximity Read ↗

The multivariate genetic architecture of psychiatric and insulin resistance multimorbidity.Semantic proximity Read ↗

Shared genetic loci between depression and cardiometabolic traits.Semantic proximity Read ↗

Clustering of major depressive disorder genetic instruments identifies distinct and directionally opposing effects on cardiometabolic riskSemantic proximity Read ↗

A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.