Article
Joint associations of cardiovascular polygenic risk and a health-related risk profile with incident cardiovascular disease among adults with depression: a UK Biobank study.
Frontiers in endocrinology - 1 Jan 2026
Lim Yohwan, Kwon Ryuk Jun
Abstract excerpt
Background: Adults with depression have higher cardiovascular disease (CVD) risk, but the joint associations of inherited CVD susceptibility and health-related risk profiles remain uncertain. We examined incident CVD according to CVD polygenic risk score (PRS) and a health-related risk profile among adults with depression. Methods: We identified 3,446 participants with depression. For participants with ICD-10...
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- Humans
- Cardiovascular Diseases
- Female
- Male
- Middle Aged
- United Kingdom
- Genetic Risk Score