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Massively parallel functional screen identifies thousands of regulatory differences in human versus chimpanzee postcranial skeletal development

2025-10-22

Abstract excerpt

Every element of the human skeleton exhibits some differences in comparison to our closest living relatives, chimpanzees. Many of these skeletal modifications underpin key events in human evolution, enabling our species to walk upright, manipulate tools with precision, and support enlarged brains. Identifying the genomic changes that underlie these features remains an outstanding challenge due to the substantial n...

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Literature Corpus work
8b3b2fad-458a-52f2-a4cc-988aeec1df49
DOI
10.1101/2025.10.21.683789
Open publication

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Massively parallel functional screen identifies thousands of regulatory differences in human versus chimpanzee postcranial skeletal developmentDOI 10.1101/2025.10.21.683789
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