Article

<i>kcnb1</i> loss-of-function in zebrafish causes neurodevelopmental and epileptic disorders associated with GABA dysregulation

2024-07-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>KEY POINTS</h4> kcnb1 is expressed in distinct cell subtypes and various regions of the central nervous system in zebrafish Brain anatomy and neuronal circuits are not disrupted in the kcnb1 loss-of-function zebrafish model Loss of kcnb1 leads to altered behavior phenotype, light and sound-induced locomotor impairments kcnb1 knock-out zebrafish exhibit increased locomotor sensitivity to...

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Literature Corpus work: 8af4d27b-3cb2-5495-b427-e911de94452e
DOI: 10.1101/2024.07.03.601913

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