Article

Zebrafish models of candidate human epilepsy-associated genes provide evidence of hyperexcitability

2024-02-08

Abstract excerpt

<h4>Summary</h4> Hundreds of novel candidate human epilepsy-associated genes have been identified thanks to advancements in next-generation sequencing and large genome-wide association studies, but establishing genetic etiology requires functional validation. We generated a list of >2200 candidate epilepsy-associated genes, of which 81 were determined suitable for the generation of loss-of-function zebrafish mode...

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Literature Corpus work: 6b121518-fb1c-5612-b6fe-8788e7696984
DOI: 10.1101/2024.02.07.579190

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